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Wiskott-Aldrich syndrome protein senses irradiation-induced DNA damage to coordinate the cell-protective Golgi dispersal response in human T and B lymphocytes
BACKGROUND: Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency disorder resulting from WASp deficiency. WAS lymphocytes manifest increased DNA damage and lymphopenia from cell death, yet how WASp influences DNA damage-linked cell survival is unknown. A recently-described mechanis...
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| Publicado no: | J Allergy Clin Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6949418/ https://ncbi.nlm.nih.gov/pubmed/31604087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.09.026 |
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