Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche

The enteric neurotransmitter acetylcholine governs important intestinal epithelial secretory and immune functions through its actions on epithelial muscarinic Gq-coupled receptors such as M3R. Its role in the regulation of intestinal stem cell function and differentiation, however, has not been clar...

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Udgivet i:Nat Commun
Main Authors: Middelhoff, Moritz, Nienhüser, Henrik, Valenti, Giovanni, Maurer, H. Carlo, Hayakawa, Yoku, Takahashi, Ryota, Kim, Woosook, Jiang, Zhengyu, Malagola, Ermanno, Cuti, Krystle, Tailor, Yagnesh, Zamechek, Leah B., Renz, Bernhard W., Quante, Michael, Yan, Kelley S., Wang, Timothy C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949263/
https://ncbi.nlm.nih.gov/pubmed/31913277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13850-7
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