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Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis

Osteoarthritis (OA) is a highly prevalent joint disorder blamed for pain and disability in older individuals. It’s commonly accepted that inflammation, apoptosis, autophagy and cellular senescence participate in the progress of OA. Protease activated receptor 2 (PAR2), a member of the G-protein coup...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Huang, Xiaojian, Ni, Bowei, Xi, Yang, Chu, Xiangyu, Zhang, Rui, You, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949101/
https://ncbi.nlm.nih.gov/pubmed/31841119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102586
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