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Divergent Mechanisms of H2AZ.1 and H2AZ.2 in PRC1-Mediated H2A Ubiquitination

The histone H2A variant H2AZ plays pivotal roles in shaping chromatin architecture and regulating gene expression. We recently identified H2AZ.2 in histone H2A lysine 119 ubiquitination (H2AK119ub)-enriched nucleosomes, but it is not known whether its highly related isoform H2AZ.1 also regulates thi...

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Bibliografiset tiedot
Päätekijät: Xiangyu Shen, Chunxu Chen, Amanda E. Jones, Xiaokun Jian, Gengsheng Cao, Hengbin Wang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2025-07-01
Sarja:Cells
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Linkit:https://www.mdpi.com/2073-4409/14/15/1133
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