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Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis

Osteoarthritis (OA) is a highly prevalent joint disorder blamed for pain and disability in older individuals. It’s commonly accepted that inflammation, apoptosis, autophagy and cellular senescence participate in the progress of OA. Protease activated receptor 2 (PAR2), a member of the G-protein coup...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Huang, Xiaojian, Ni, Bowei, Xi, Yang, Chu, Xiangyu, Zhang, Rui, You, Hongbo
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949101/
https://ncbi.nlm.nih.gov/pubmed/31841119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102586
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