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Aberrant ER Stress Induced Neuronal-IFNβ Elicits White Matter Injury Due to Microglial Activation and T-Cell Infiltration after TBI

Persistent endoplasmic reticulum (ER) stress in neurons is associated with activation of inflammatory cells and subsequent neuroinflammation following traumatic brain injury (TBI); however, the underlying mechanism remains elusive. We found that induction of neuronal-ER stress, which was mostly char...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sen, Tanusree, Saha, Pampa, Gupta, Rajaneesh, Foley, Lesley M., Jiang, Tong, Abakumova, Olena S., Hitchens, T. Kevin, Sen, Nilkantha
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948950/
https://ncbi.nlm.nih.gov/pubmed/31694961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0718-19.2019
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