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Activation of PERK Elicits Memory Impairment through Inactivation of CREB and Downregulation of PSD95 After Traumatic Brain Injury
The PKR-like ER kinase (PERK), a transmembrane protein, resides in the endoplasmic reticulum (ER). Its activation serves as a key sensor of ER stress, which has been implicated in traumatic brain injury (TBI). The loss of memory is one of the most common symptoms after TBI, but the precise role of P...
में बचाया:
| में प्रकाशित: | J Neurosci |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Society for Neuroscience
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473207/ https://ncbi.nlm.nih.gov/pubmed/28522733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2343-16.2017 |
| टैग : |
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