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Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis

Previous work has reported the important links between cellular bioenergetics and the development of chronic kidney disease, highlighting the potential for targeting metabolic functions to regulate disease progression. More recently, it has been shown that alterations in fatty acid oxidation (FAO) c...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Price, Nathan L., Miguel, Verónica, Ding, Wen, Singh, Abhishek K., Malik, Shipra, Rotllan, Noemi, Moshnikova, Anna, Toczek, Jakub, Zeiss, Caroline, Sadeghi, Mehran M., Arias, Noemi, Baldán, Ángel, Andreev, Oleg A., Rodríguez-Puyol, Diego, Bahal, Raman, Reshetnyak, Yana K., Suárez, Yajaira, Fernández-Hernando, Carlos, Lamas, Santiago
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948871/
https://ncbi.nlm.nih.gov/pubmed/31613798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131102
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