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Probe for the measurement of cell surface pH in vivo and ex vivo

We have developed a way to measure cell surface pH by positioning a pH-sensitive fluorescent dye, seminaphtharhodafluor (SNARF), conjugated to the pH low insertion peptide (pHLIP). It has been observed that many diseased tissues are acidic and that tumors are especially so. A combination of effects...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Anderson, Michael, Moshnikova, Anna, Engelman, Donald M., Reshetnyak, Yana K., Andreev, Oleg A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961157/
https://ncbi.nlm.nih.gov/pubmed/27382181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608247113
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