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Investigation of PLGA nanoparticles in conjunction with nuclear localization sequence for enhanced delivery of antimiR phosphorothioates in cancer cells in vitro

Numerous first generation phosphorothioates (PS) and their derivatives have shown promise targeting mRNA for therapeutic applications and also gained market approval for their use as a drug. However, PS have not been explored for targeting microRNAs (miRNAs or miRs). In particular, efficient deliver...

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Bibliografiske detaljer
Udgivet i:J Nanobiotechnology
Main Authors: Malik, Shipra, Bahal, Raman
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475967/
https://ncbi.nlm.nih.gov/pubmed/31010426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0490-2
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