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Murine osteosarcoma primary tumour growth and metastatic progression is maintained after marked suppression of serum insulin-like growth factor I

The insulin-like growth factor I (IGF-I) signaling pathway has been shown to play an important role in several aspects of cancer biology, including metastasis. The aim of this study was to define the contribution of serum (endocrine) and local (tumour microenvironment) IGF-I on osteosarcoma tumour g...

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Publicat a:Int J Cancer
Autors principals: Hong, Sung-Hyeok, Briggs, Joseph, Newman, Rachel, Hoffman, Karen, Mendoza, Arnulfo, LeRoith, Derek, Helman, Lee, Yakar, Shoshana, Khanna, Chand
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948843/
https://ncbi.nlm.nih.gov/pubmed/19132750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24169
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