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Murine osteosarcoma primary tumour growth and metastatic progression is maintained after marked suppression of serum insulin-like growth factor I

The insulin-like growth factor I (IGF-I) signaling pathway has been shown to play an important role in several aspects of cancer biology, including metastasis. The aim of this study was to define the contribution of serum (endocrine) and local (tumour microenvironment) IGF-I on osteosarcoma tumour g...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Hong, Sung-Hyeok, Briggs, Joseph, Newman, Rachel, Hoffman, Karen, Mendoza, Arnulfo, LeRoith, Derek, Helman, Lee, Yakar, Shoshana, Khanna, Chand
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948843/
https://ncbi.nlm.nih.gov/pubmed/19132750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24169
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