Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell

Human cancer cells were eradicated by adoptive transfer of T cells transduced with a chimeric antigen receptor (CAR) made from an antibody (237Ab) that is highly specific for the murine Tn-glycosylated podoplanin (Tn-PDPN). The objectives were to determine the specificity of these CAR-transduced T (...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: He, Yanran, Schreiber, Karin, Wolf, Steven P., Wen, Frank, Steentoft, Catharina, Zerweck, Jonathan, Steiner, Madeline, Sharma, Preeti, Shepard, H. Michael, Posey, Avery, June, Carl H., Mandel, Ulla, Clausen, Henrik, Leisegang, Matthias, Meredith, Stephen C., Kranz, David M., Schreiber, Hans
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948763/
https://ncbi.nlm.nih.gov/pubmed/31672936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130416
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk