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Protein interaction networks revealed by proteome coevolution

Residue-residue coevolution has been observed across a number of protein-protein interfaces, but the extent of residue coevolution between protein families on the whole-proteome scale has not been systematically studied. We investigate coevolution between 5.4 million pairs of proteins in Escherichia...

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Bibliografski detalji
Izdano u:Science
Glavni autori: Cong, Qian, Anishchenko, Ivan, Ovchinnikov, Sergey, Baker, David
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948103/
https://ncbi.nlm.nih.gov/pubmed/31296772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw6718
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