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Elevated choline kinase α–mediated choline metabolism supports the prolonged survival of TRAF3-deficient B lymphocytes

Specific deletion of the tumor suppressor TRAF3 from B lymphocytes in mice leads to the prolonged survival of mature B cells and expanded B cell compartments in secondary lymphoid organs. In the present study, we investigated the metabolic basis of TRAF3-mediated regulation of B cell survival by emp...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Gokhale, Samantha, Lu, Wenyun, Zhu, Sining, Liu, Yingying, Hart, Ronald P., Rabinowitz, Joshua D., Xie, Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946882/
https://ncbi.nlm.nih.gov/pubmed/31826940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900658
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