Chargement en cours...

Elevated choline kinase α–mediated choline metabolism supports the prolonged survival of TRAF3-deficient B lymphocytes

Specific deletion of the tumor suppressor TRAF3 from B lymphocytes in mice leads to the prolonged survival of mature B cells and expanded B cell compartments in secondary lymphoid organs. In the present study, we investigated the metabolic basis of TRAF3-mediated regulation of B cell survival by emp...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Gokhale, Samantha, Lu, Wenyun, Zhu, Sining, Liu, Yingying, Hart, Ronald P., Rabinowitz, Joshua D., Xie, Ping
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946882/
https://ncbi.nlm.nih.gov/pubmed/31826940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900658
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!