TRAF2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice()

We have previously shown that transgenic mice expressing in B lymphocytes both BCL-2 and a TRAF2 mutant lacking the RING and zinc finger domains (TRAF2DN) develop small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) with high incidence. Further analysis of the expression of TRAF2...

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Autori principali: Pérez-Chacón, Gema, Llobet, David, Pardo, Constanza, Pindado, Jose, Choi, Yongwon, Reed, John C., Zapata, Juan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526975/
https://ncbi.nlm.nih.gov/pubmed/22711886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200814
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