Pathogen-boosted adoptive cell transfer therapy induces endogenous antitumor immunity through antigen spreading

Loss of target antigens in tumor cells has become one of the major hurdles limiting the efficacy of adoptive cell therapy (ACT)-based immunotherapies. The optimal approach to overcome this challenge includes broadening the immune response from the initially targeted tumor-associated antigen (TAA) to...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Xin, Gang, Khatun, Achia, Topchyan, Paytsar, Zander, Ryan, Volberding, Peter J, Chen, Yao, Shen, Jian, Fu, Chunmei, Jiang, Aimin, See, William A., Cui, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946848/
https://ncbi.nlm.nih.gov/pubmed/31719059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0251
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