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Pathogen boosted adoptive cell transfer immunotherapy to treat solid tumors

Because of insufficient migration and antitumor function of transferred T cells, especially inside the immunosuppressive tumor microenvironment (TME), the efficacy of adoptive cell transfer (ACT) is much curtailed in treating solid tumors. To overcome these challenges, we sought to reenergize ACT (R...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xin, Gang, Schauder, David M., Jing, Weiqing, Jiang, Aimin, Joshi, Nikhil S., Johnson, Bryon, Cui, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278465/
https://ncbi.nlm.nih.gov/pubmed/28069963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614315114
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