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Antibiotic treatment ameliorates Ten-eleven Translocation 2 (TET2) loss-of-function associated hematological malignancies

TET2 is among the most frequently mutated genes in hematological malignancies, as well as in healthy individuals with clonal hematopoiesis. Inflammatory stress is known to promote the expansion of Tet2-deficient hematopoietic stem cells, as well as the initiation of pre-leukemic conditions. Infectio...

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Bibliografiske detaljer
Udgivet i:Cancer Lett
Main Authors: Zeng, Hongxiang, He, Hailan, Guo, Lei, Li, Jia, Lee, Minjung, Han, Wei, Guzman, Anna G., Zang, Shengbing, Zhou, Yubin, Zhang, Xiaotian, Goodell, Margaret A., King, Katherine Y., Sun, Deqiang, Huang, Yun
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945766/
https://ncbi.nlm.nih.gov/pubmed/31563562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.09.013
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