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Increased levels of XPA might be the basis of cisplatin resistance in germ cell tumours
BACKGROUND: Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be caused by an increased capacity to repair CDDP-induced DNA da...
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| Izdano u: | BMC Cancer |
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| Glavni autori: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6945513/ https://ncbi.nlm.nih.gov/pubmed/31906898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6496-1 |
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