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βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

BACKGROUND: WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. METHODS: Surgical specimens from 247 patients were analyzed. Βcatenin ex...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Cancer
Hauptverfasser: Chovanec, Michal, Cierna, Zuzana, Miskovska, Viera, Machalekova, Katarina, Kalavska, Katarina, Rejlekova, Katarina, Svetlovska, Daniela, Macak, Dusan, Spanik, Stanislav, Kajo, Karol, Babal, Pavel, Mego, Michal, Mardiak, Jozef
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215644/
https://ncbi.nlm.nih.gov/pubmed/30390643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4929-x
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