βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

BACKGROUND: WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. METHODS: Surgical specimens from 247 patients were analyzed. Βcatenin ex...

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Vydáno v:BMC Cancer
Hlavní autoři: Chovanec, Michal, Cierna, Zuzana, Miskovska, Viera, Machalekova, Katarina, Kalavska, Katarina, Rejlekova, Katarina, Svetlovska, Daniela, Macak, Dusan, Spanik, Stanislav, Kajo, Karol, Babal, Pavel, Mego, Michal, Mardiak, Jozef
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215644/
https://ncbi.nlm.nih.gov/pubmed/30390643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4929-x
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