Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

BACKGROUND: 2-Hydroxybenzylamine (2-HOBA) is a selective dicarbonyl electrophile scavenger being developed as a nutritional supplement to help protect against the development of conditions associated with dicarbonyl electrophile formation, such as the cognitive decline observed with Mild Cognitive I...

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Pubblicato in:BMC Pharmacol Toxicol
Autori principali: Pitchford, Lisa M., Driver, Patricia M., Fuller, John C., Akers, Wendell S., Abumrad, Naji N., Amarnath, Venkataraman, Milne, Ginger L., Chen, Sheau-Chiann, Ye, Fei, Roberts, L. Jackson, Shoemaker, M. Benjamin, Oates, John A., Rathmacher, John A., Boutaud, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945443/
https://ncbi.nlm.nih.gov/pubmed/31907026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-0382-y
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