Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway(✰)

BACKGROUND: Aortic dissection is a severe inflammatory vascular disease with high mortality and limited therapeutic options. The hallmarks of aortic dissection comprise aortic inflammatory cell infiltration and elastic fiber disruption, highlighting the involvement of macrophage. Here a role for mac...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Lian, Guan, Li, Xiaopeng, Zhang, Linqi, Zhang, Yangming, Sun, Lulu, Zhang, Xiujuan, Liu, Huiying, Pang, Yanli, Kong, Wei, Zhang, Tao, Wang, Xian, Jiang, Changtao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
Onderwerpen:
Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945268/
https://ncbi.nlm.nih.gov/pubmed/31640947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.041
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