Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway(✰)

BACKGROUND: Aortic dissection is a severe inflammatory vascular disease with high mortality and limited therapeutic options. The hallmarks of aortic dissection comprise aortic inflammatory cell infiltration and elastic fiber disruption, highlighting the involvement of macrophage. Here a role for mac...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Lian, Guan, Li, Xiaopeng, Zhang, Linqi, Zhang, Yangming, Sun, Lulu, Zhang, Xiujuan, Liu, Huiying, Pang, Yanli, Kong, Wei, Zhang, Tao, Wang, Xian, Jiang, Changtao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945268/
https://ncbi.nlm.nih.gov/pubmed/31640947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.041
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