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Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway(✰)
BACKGROUND: Aortic dissection is a severe inflammatory vascular disease with high mortality and limited therapeutic options. The hallmarks of aortic dissection comprise aortic inflammatory cell infiltration and elastic fiber disruption, highlighting the involvement of macrophage. Here a role for mac...
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| Veröffentlicht in: | EBioMedicine |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6945268/ https://ncbi.nlm.nih.gov/pubmed/31640947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.041 |
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