Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway(✰)

BACKGROUND: Aortic dissection is a severe inflammatory vascular disease with high mortality and limited therapeutic options. The hallmarks of aortic dissection comprise aortic inflammatory cell infiltration and elastic fiber disruption, highlighting the involvement of macrophage. Here a role for mac...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Lian, Guan, Li, Xiaopeng, Zhang, Linqi, Zhang, Yangming, Sun, Lulu, Zhang, Xiujuan, Liu, Huiying, Pang, Yanli, Kong, Wei, Zhang, Tao, Wang, Xian, Jiang, Changtao
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945268/
https://ncbi.nlm.nih.gov/pubmed/31640947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.041
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