Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway(✰)

BACKGROUND: Aortic dissection is a severe inflammatory vascular disease with high mortality and limited therapeutic options. The hallmarks of aortic dissection comprise aortic inflammatory cell infiltration and elastic fiber disruption, highlighting the involvement of macrophage. Here a role for mac...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Lian, Guan, Li, Xiaopeng, Zhang, Linqi, Zhang, Yangming, Sun, Lulu, Zhang, Xiujuan, Liu, Huiying, Pang, Yanli, Kong, Wei, Zhang, Tao, Wang, Xian, Jiang, Changtao
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945268/
https://ncbi.nlm.nih.gov/pubmed/31640947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.041
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