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SREBP1 promotes 5-FU resistance in colorectal cancer cells by inhibiting the expression of caspase7

Background: The role of lipid metabolism played in cancer cell growth attracts more attention. SREBP1 is a common lipid regulatory factor. It has been reported that SREBP1 can promote tumor cell resistance. The aim of this study was to investigate its role in chemoresistance of colorectal cancer (CR...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Gao, Yuyan, Zhao, Qi, Mu, Xiaoqin, Zhu, Huifen, Liu, Binbin, Yao, Bingqing, Liu, Xinyi, Xue, Wenhan, Wang, Bo, Liu, Shulin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945170/
https://ncbi.nlm.nih.gov/pubmed/31933924
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