SREBP1 promotes the invasion of colorectal cancer accompanied upregulation of MMP7 expression and NF-κB pathway activation

BACKGROUND: Sterol-regulatory element binding protein 1 (SREBP1), an intracellular cholesterol sensor located in the endoplasmic reticulum, regulates the intracellular cholesterol by the Insig-Srebp-Scap pathway. Over-expression of SREBP1 can cause dyslipidemia. SREBP1 can regulate the metabolic pat...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gao, Yuyan, Nan, Xianxiu, Shi, Xinjue, Mu, Xiaoqin, Liu, Binbin, Zhu, Huifen, Yao, Bingqing, Liu, Xinyi, Yang, Tianyue, Hu, Yiting, Liu, Shulin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626379/
https://ncbi.nlm.nih.gov/pubmed/31299935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5904-x
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