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CYP17A1 and Androgen-Receptor Expression in Prostate Carcinoma Tissues and Cancer Cell Lines

BACKGROUND: CYP17A1 is involved in the steroidogenesis of dehydroepiandrosterone and androstenedione. CYP17A is a target for the hormonal treatment of prostate cancer (PCa). OBJECTIVES: To investigate the role of CYP17A1 as a driver of PCa growth. MATERIALS AND METHODS: We examined the expression of...

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Detalhes bibliográficos
Publicado no:Curr Urol
Main Authors: Giatromanolaki, Alexandra, Fasoulaki, Virginia, Kalamida, Dimitra, Mitrakas, Achilleas, Kakouratos, Christos, Lialiaris, Theodoros, Koukourakis, Michael I.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944932/
https://ncbi.nlm.nih.gov/pubmed/31933595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499276
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