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First identified Korean family with Tatton-Brown-Rahman Syndrome caused by the novel DNMT3A variant c.118G>C p.(Glu40Gln)

Tatton-Brown-Rahman Syndrome (TBRS), an overgrowth syndrome caused by heterozygous mutation of DNMT3A, first was described in 2014. Approximately 60 DNMT3A variants, including 32 missense variants, have been reported, with most missense mutations located on the DNMT3A functional domains. Autosomal d...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Pediatr Endocrinol Metab
Hauptverfasser: Lee, Cha Gon, Jang, Ja-Hyun, Seo, Ji-Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society of Pediatric Endocrinology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944862/
https://ncbi.nlm.nih.gov/pubmed/31905446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6065/apem.2019.24.4.253
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