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First identified Korean family with Tatton-Brown-Rahman Syndrome caused by the novel DNMT3A variant c.118G>C p.(Glu40Gln)

Tatton-Brown-Rahman Syndrome (TBRS), an overgrowth syndrome caused by heterozygous mutation of DNMT3A, first was described in 2014. Approximately 60 DNMT3A variants, including 32 missense variants, have been reported, with most missense mutations located on the DNMT3A functional domains. Autosomal d...

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Detalhes bibliográficos
Publicado no:Ann Pediatr Endocrinol Metab
Main Authors: Lee, Cha Gon, Jang, Ja-Hyun, Seo, Ji-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Pediatric Endocrinology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944862/
https://ncbi.nlm.nih.gov/pubmed/31905446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6065/apem.2019.24.4.253
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