Effects of the poly(ADP-ribose) polymerase inhibitor olaparib in cerulein-induced pancreatitis

OBJECTIVE: Activation of the constitutive nuclear and mitochondrial enzyme poly(ADP-ribose) polymerase (PARP) has been implicated in the pathogenesis of cell dysfunction, inflammation and organ failure in various forms of critical illness. The objective of our study was to evaluate the efficacy and...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Ahmad, Akbar, Szczesny, Bartosz, Törö, Gábor, Marcatti, Michela, Druzhyna, Nadiya, Liaudet, Lucas, Tarantini, Stefano, Salomao, Reinaldo, Soriano, Francisco Garcia, Szabo, Csaba
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944774/
https://ncbi.nlm.nih.gov/pubmed/31274831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001402
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