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Function of the MYND Domain and C-Terminal Region in Regulating the Subcellular Localization and Catalytic Activity of the SMYD Family Lysine Methyltransferase Set5

SMYD lysine methyltransferases target histones and nonhistone proteins for methylation and are critical regulators of muscle development and implicated in neoplastic transformation. They are characterized by a split catalytic SET domain and an intervening MYND zinc finger domain, as well as an exten...

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Pubblicato in:Mol Cell Biol
Autori principali: Jaiswal, Deepika, Turniansky, Rashi, Moresco, James J., Ikram, Sabeen, Ramaprasad, Ganesh, Akinwole, Assefa, Wolf, Julie, Yates, John R., Green, Erin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944473/
https://ncbi.nlm.nih.gov/pubmed/31685550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00341-19
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