GC content shapes mRNA storage and decay in human cells

mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing of broadly acting mRNA decay and repression factors, and with available CL...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Courel, Maïté, Clément, Yves, Bossevain, Clémentine, Foretek, Dominika, Vidal Cruchez, Olivia, Yi, Zhou, Bénard, Marianne, Benassy, Marie-Noëlle, Kress, Michel, Vindry, Caroline, Ernoult-Lange, Michèle, Antoniewski, Christophe, Morillon, Antonin, Brest, Patrick, Hubstenberger, Arnaud, Roest Crollius, Hugues, Standart, Nancy, Weil, Dominique
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Chromosomes and Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944446/
https://ncbi.nlm.nih.gov/pubmed/31855182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49708
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