The DDX6–4E-T interaction mediates translational repression and P-body assembly

4E-Transporter binds eIF4E via its consensus sequence YXXXXLΦ, shared with eIF4G, and is a nucleocytoplasmic shuttling protein found enriched in P-(rocessing) bodies. 4E-T inhibits general protein synthesis by reducing available eIF4E levels. Recently, we showed that 4E-T bound to mRNA however repre...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kamenska, Anastasiia, Simpson, Clare, Vindry, Caroline, Broomhead, Helen, Bénard, Marianne, Ernoult-Lange, Michèle, Lee, Benjamin P., Harries, Lorna W., Weil, Dominique, Standart, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291280/
https://ncbi.nlm.nih.gov/pubmed/27342281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw565
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