GC content shapes mRNA storage and decay in human cells

mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing of broadly acting mRNA decay and repression factors, and with available CL...

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Vydáno v:eLife
Hlavní autoři: Courel, Maïté, Clément, Yves, Bossevain, Clémentine, Foretek, Dominika, Vidal Cruchez, Olivia, Yi, Zhou, Bénard, Marianne, Benassy, Marie-Noëlle, Kress, Michel, Vindry, Caroline, Ernoult-Lange, Michèle, Antoniewski, Christophe, Morillon, Antonin, Brest, Patrick, Hubstenberger, Arnaud, Roest Crollius, Hugues, Standart, Nancy, Weil, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Chromosomes and Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944446/
https://ncbi.nlm.nih.gov/pubmed/31855182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49708
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