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BRCA1 and p53 regulate critical prostate cancer pathways
BACKGROUND: Loss or mutations of the BRCA1 gene are associated with increased risk of breast and ovarian cancers and with prostate cancer (PCa) aggressiveness. Previously, we identified GADD153 as a target of BRCA1 protein, which increases doxorubicin sensitivity in human p53 −/− PCa cells (PC3). Co...
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| Publicat a: | Prostate Cancer Prostatic Dis |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944434/ https://ncbi.nlm.nih.gov/pubmed/23670255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pcan.2013.12 |
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