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Gene Knock-Ins in Drosophila Using Homology-Independent Insertion of Universal Donor Plasmids

Targeted genomic knock-ins are a valuable tool to probe gene function. However, knock-in methods involving homology-directed repair (HDR) can be laborious. Here, we adapt the mammalian CRISPaint [clustered regularly interspaced short palindromic repeat (CRISPR)-assisted insertion tagging] homology-i...

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Bibliographic Details
Published in:Genetics
Main Authors: Bosch, Justin A., Colbeth, Ryan, Zirin, Jonathan, Perrimon, Norbert
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944404/
https://ncbi.nlm.nih.gov/pubmed/31685521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302819
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