Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

Cholesteryl ester transfer protein (CETP) inhibition reduces vascular event risk, but confusion surrounds its effects on low-density lipoprotein (LDL) cholesterol. Here, we clarify associations of genetic inhibition of CETP on detailed lipoprotein measures and compare those to genetic inhibition of...

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Udgivet i:PLoS Biol
Main Authors: Kettunen, Johannes, Holmes, Michael V., Allara, Elias, Anufrieva, Olga, Ohukainen, Pauli, Oliver-Williams, Clare, Wang, Qin, Tillin, Therese, Hughes, Alun D., Kähönen, Mika, Lehtimäki, Terho, Viikari, Jorma, Raitakari, Olli T., Salomaa, Veikko, Järvelin, Marjo-Riitta, Perola, Markus, Davey Smith, George, Chaturvedi, Nish, Danesh, John, Di Angelantonio, Emanuele, Butterworth, Adam S., Ala-Korpela, Mika
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944381/
https://ncbi.nlm.nih.gov/pubmed/31860674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000572
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