A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study

INTRODUCTION: Circulating cell-free DNA (cf-DNA) is a useful indicator of cell death, and it can also be used to predict outcomes in various clinical disorders. Several innate immune mechanisms are known to be involved in eliminating DNA and chromatin-related material as part of the inhibition of po...

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Main Authors: Jylhävä, Juulia, Lyytikäinen, Leo-Pekka, Kähönen, Mika, Hutri-Kähönen, Nina, Kettunen, Johannes, Viikari, Jorma, Raitakari, Olli T., Lehtimäki, Terho, Hurme, Mikko
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325226/
https://ncbi.nlm.nih.gov/pubmed/22511988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035426
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