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OH-2, a hyperdiploid myeloma cell line without an IGH translocation, has a complex translocation juxtaposing MYC near MAFB and the IGK locus
Multiple myeloma can be classified into hyperdiploid (HRD) (with 48–74 chromosomes) and nonhyperdiploid tumors (usually with immunoglobulin heavy chain translocations). The OH-2 human myeloma cell line (HMCL) retains the same HRD genotype as the primary tumor, with extra copies of chromosomes 3, 7,...
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| 出版年: | Leuk Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944273/ https://ncbi.nlm.nih.gov/pubmed/19395026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.03.001 |
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