OH-2, a hyperdiploid myeloma cell line without an IGH translocation, has a complex translocation juxtaposing MYC near MAFB and the IGK locus

Multiple myeloma can be classified into hyperdiploid (HRD) (with 48–74 chromosomes) and nonhyperdiploid tumors (usually with immunoglobulin heavy chain translocations). The OH-2 human myeloma cell line (HMCL) retains the same HRD genotype as the primary tumor, with extra copies of chromosomes 3, 7,...

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Publicado no:Leuk Res
Main Authors: Våtsveen, Thea Kristin, Tian, Erming, Kresse, Stine H., Meza-Zepeda, Leonardo A., Gabrea, Ana, Glebov, Oleg, Dai, Hong Yan, Sundan, Anders, Kuehl, W. Michael, Børset, Magne
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944273/
https://ncbi.nlm.nih.gov/pubmed/19395026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.03.001
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