OH-2, a hyperdiploid myeloma cell line without an IGH translocation, has a complex translocation juxtaposing MYC near MAFB and the IGK locus

Multiple myeloma can be classified into hyperdiploid (HRD) (with 48–74 chromosomes) and nonhyperdiploid tumors (usually with immunoglobulin heavy chain translocations). The OH-2 human myeloma cell line (HMCL) retains the same HRD genotype as the primary tumor, with extra copies of chromosomes 3, 7,...

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Pubblicato in:Leuk Res
Autori principali: Våtsveen, Thea Kristin, Tian, Erming, Kresse, Stine H., Meza-Zepeda, Leonardo A., Gabrea, Ana, Glebov, Oleg, Dai, Hong Yan, Sundan, Anders, Kuehl, W. Michael, Børset, Magne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944273/
https://ncbi.nlm.nih.gov/pubmed/19395026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.03.001
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