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Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2
The p53 tumor suppressor protein is a transcription factor that plays a prominent role in protecting cells from malignant transformation. Protein levels of p53 and its transcriptional activity are tightly regulated by the ubiquitin E3 ligase MDM2, the gene expression of which is transcriptionally re...
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| 出版年: | Mol Oncol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944118/ https://ncbi.nlm.nih.gov/pubmed/31665549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12592 |
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