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Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

The p53 tumor suppressor protein is a transcription factor that plays a prominent role in protecting cells from malignant transformation. Protein levels of p53 and its transcriptional activity are tightly regulated by the ubiquitin E3 ligase MDM2, the gene expression of which is transcriptionally re...

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Bibliografski detalji
Izdano u:Mol Oncol
Glavni autori: García‐Cano, Jesús, Sánchez‐Tena, Susana, Sala‐Gaston, Joan, Figueras, Agnès, Viñals, Francesc, Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944118/
https://ncbi.nlm.nih.gov/pubmed/31665549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12592
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