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The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

A mutation in the HERC2 gene has been linked to a severe neurodevelopmental disorder with similarities to the Angelman syndrome. This gene codifies a protein with ubiquitin ligase activity that regulates the activity of tumor protein p53 and is involved in important cellular processes such as DNA re...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Cubillos-Rojas, Monica, Schneider, Taiane, Hadjebi, Ouadah, Pedrazza, Leonardo, de Oliveira, Jarbas Rodrigues, Langa, Francina, Guénet, Jean-Louis, Duran, Joan, de Anta, Josep Maria, Alcántara, Soledad, Ruiz, Rocio, Pérez-Villegas, Eva María, Aguilar, Francisco J., Carrión, Ángel M., Armengol, Jose Angel, Baple, Emma, Crosby, Andrew H., Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302898/
https://ncbi.nlm.nih.gov/pubmed/27528230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11270
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