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The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation
The RAF/MEK/ERK cascade is a conserved intracellular signaling pathway that controls fundamental cellular processes including growth, proliferation, differentiation, survival and migration. Aberrant regulation of this signaling pathway has long been associated with human cancers. A major point of re...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101136/ https://ncbi.nlm.nih.gov/pubmed/30140388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25847 |
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