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The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
HERC1 is a ubiquitin ligase protein, which, when mutated, induces several malformations and intellectual disability in humans. The animal model of HERC1 mutation is the mouse tambaleante characterized by: (1) overproduction of the protein; (2) cerebellar Purkinje cells death by autophagy; (3) dysreg...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7374096/ https://ncbi.nlm.nih.gov/pubmed/32694577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68970-8 |
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