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miR‐15a‐5p, miR‐15b‐5p, and miR‐16‐5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Neuroblastoma (NB) is the most common extracranial solid malignancy in children. Despite current aggressive treatment regimens, the prognosis for high‐risk NB patients remains poor, with the survival of less than 40%. Amplification/stabilization of MYCN oncogene, in NB is associated with a high risk...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Chava, Srinivas, Reynolds, C. Patrick, Pathania, Anup S., Gorantla, Santhi, Poluektova, Larisa Y., Coulter, Don W., Gupta, Subash C., Pandey, Manoj K., Challagundla, Kishore B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944109/
https://ncbi.nlm.nih.gov/pubmed/31637848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12588
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