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miR‐15a‐5p, miR‐15b‐5p, and miR‐16‐5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Neuroblastoma (NB) is the most common extracranial solid malignancy in children. Despite current aggressive treatment regimens, the prognosis for high‐risk NB patients remains poor, with the survival of less than 40%. Amplification/stabilization of MYCN oncogene, in NB is associated with a high risk...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Chava, Srinivas, Reynolds, C. Patrick, Pathania, Anup S., Gorantla, Santhi, Poluektova, Larisa Y., Coulter, Don W., Gupta, Subash C., Pandey, Manoj K., Challagundla, Kishore B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944109/
https://ncbi.nlm.nih.gov/pubmed/31637848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12588
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