miR‐15a‐5p, miR‐15b‐5p, and miR‐16‐5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Neuroblastoma (NB) is the most common extracranial solid malignancy in children. Despite current aggressive treatment regimens, the prognosis for high‐risk NB patients remains poor, with the survival of less than 40%. Amplification/stabilization of MYCN oncogene, in NB is associated with a high risk...

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Vydáno v:Mol Oncol
Hlavní autoři: Chava, Srinivas, Reynolds, C. Patrick, Pathania, Anup S., Gorantla, Santhi, Poluektova, Larisa Y., Coulter, Don W., Gupta, Subash C., Pandey, Manoj K., Challagundla, Kishore B.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944109/
https://ncbi.nlm.nih.gov/pubmed/31637848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12588
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