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Soybean lecithin stabilizes disulfiram nanosuspensions with a high drug-loading content: remarkably improved antitumor efficacy

Disulfiram (DSF) has been considered as “Repurposing drug” in cancer therapy in recent years based on its good antitumor efficacy. DSF is traditionally used as an oral drug in the treatment of alcoholism. To overcome its rapid degradation and instability, DSF nanosuspensions (DSF/SPC-NSps) were prep...

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Vydáno v:J Nanobiotechnology
Hlavní autoři: Li, Haowen, Liu, Biao, Ao, Hui, Fu, Jingxin, Wang, Yian, Feng, Yue, Guo, Yifei, Wang, Xiangtao
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943900/
https://ncbi.nlm.nih.gov/pubmed/31907045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0565-0
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